Human SRGAP3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	SRGAP3
Locus ID	9901
Kit Components	GA106687G1, SRGAP3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA106687G2, SRGAP3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA106687G3, SRGAP3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001033116, NM_001033117, NM_014850
Synonyms	ARHGAP14; KIAA0411; MEGAP; SLIT-ROBO Rho GTPase-activating protein 3; SLIT-ROBO Rho GTPase activating protein 2; SLIT-ROBO Rho GTPase activating protein 3; SRGAP2; WAVE-associated Rac GTPase activating protein; WRP; WRP, MEGAP, SRGAP2, ARHGAP14, KIAA0411
Summary	GTPase-activating protein for RAC1 and perhaps Cdc42, but not for RhoA small GTPase. May attenuate RAC1 signaling in neurons.[UniProtKB/Swiss-Prot Function]

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