Human AP180 (SNAP91) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	SNAP91
Locus ID	9892
Kit Components	GA106679G1, AP180 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA106679G2, AP180 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA106679G3, AP180 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001242792, NM_001242793, NM_001242794, NM_001256717, NM_001256718, NM_014841, NR_026669, NM_001363677
Synonyms	AP180; CALM
Summary	Adaptins are components of the adapter complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. Binding of AP180 to clathrin triskelia induces their assembly into 60-70 nm coats (By similarity).[UniProtKB/Swiss-Prot Function]

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