Human Smad Interacting Protein 1 (ZEB2) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ZEB2
Locus ID	9839
Kit Components	GA106632G1, Smad Interacting Protein 1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA106632G2, Smad Interacting Protein 1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA106632G3, Smad Interacting Protein 1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001171653, NM_014795, NR_033258
Synonyms	HSPC082; SIP-1; SIP1; SMADIP1; ZFHX1B
Summary	The protein encoded by this gene is a member of the Zfh1 family of 2-handed zinc finger/homeodomain proteins. It is located in the nucleus and functions as a DNA-binding transcriptional repressor that interacts with activated SMADs. Mutations in this gene are associated with Hirschsprung disease/Mowat-Wilson syndrome. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Jan 2010]

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