Human IBP160 (AQR) activation kit by CRISPRa

CAT#: GA106524

AQR CRISPRa kit - CRISPR gene activation of human aquarius intron-binding spliceosomal factor



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

Product images

经常一起买 (2)
AQR Rabbit polyclonal Antibody
    • 100 ul

CNY 1,999.00
CNY 3,280.00


AQR (Myc-DDK-tagged)-Human aquarius homolog (mouse) (AQR)
    • 10 ug

CNY 10,160.00

Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol AQR
Locus ID 9716
Kit Components

GA106524G1, IBP160 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA106524G2, IBP160 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA106524G3, IBP160 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_014691
Synonyms fSAP164; IBP160
Summary Involved in pre-mRNA splicing as component of the spliceosome (PubMed:11991638, PubMed:25599396, PubMed:28502770, PubMed:28076346). Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis (PubMed:16949364). Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly (PubMed:16949364). May act by helping the folding of the snoRNA sequence. Binds to intron of pre-mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing (PubMed:16949364). Has ATP-dependent RNA helicase activity and can unwind double-stranded RNA molecules with a 3' overhang (in vitro) (PubMed:25599396).[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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