Human Synphilin 1 (SNCAIP) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	SNCAIP
Locus ID	9627
Kit Components	GA106447G1, Synphilin 1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA106447G2, Synphilin 1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA106447G3, Synphilin 1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001242935, NM_001308100, NM_001308105, NM_001308106, NM_001308107, NM_001308108, NM_001308109, NM_005460, NR_131761, NR_131762, N21998
Synonyms	Sph1; SYPH1
Summary	This gene encodes a protein containing several protein-protein interaction domains, including ankyrin-like repeats, a coiled-coil domain, and an ATP/GTP-binding motif. The encoded protein interacts with alpha-synuclein in neuronal tissue and may play a role in the formation of cytoplasmic inclusions and neurodegeneration. A mutation in this gene has been associated with Parkinson's disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]

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