Human SH3BP5 activation kit by CRISPRa

CAT#: GA106324

SH3BP5 CRISPRa kit - CRISPR gene activation of human SH3 domain binding protein 5



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

Product images

经常一起买 (3)
Rabbit Polyclonal Anti-SH3BP5 Antibody
    • 100 ul

CNY 5,250.00


SH3BP5 (Myc-DDK-tagged)-Human SH3-domain binding protein 5 (BTK-associated) (SH3BP5), transcript variant 1
    • 10 ug

CNY 3,656.00
CNY 3,990.00


Rabbit Polyclonal Anti-SH3BP5 Antibody
    • 100 ul

CNY 5,250.00

Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol SH3BP5
Locus ID 9467
Kit Components

GA106324G1, SH3BP5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA106324G2, SH3BP5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA106324G3, SH3BP5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001018009, NM_004844
Synonyms SAB; SH3BP-5
Summary Functions as guanine nucleotide exchange factor (GEF) with specificity for RAB11A and RAB25 (PubMed:26506309, PubMed:30217979). Inhibits the auto- and transphosphorylation activity of BTK. Plays a negative regulatory role in BTK-related cytoplasmic signaling in B-cells. May be involved in BCR-induced apoptotic cell death.[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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