Human STOML1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	STOML1
Locus ID	9399
Kit Components	GA106271G1, STOML1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA106271G2, STOML1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA106271G3, STOML1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001256672, NM_001256673, NM_001256674, NM_001256675, NM_001256676, NM_001256677, NM_001324226, NM_001324227, NM_001324228, NM_001324229, NM_001324230, NM_004809
Synonyms	hUNC-24; SLP-1; STORP
Summary	May play a role in cholesterol transfer to late endosomes (PubMed:19696025). May play a role in modulating membrane acid-sensing ion channels. Can specifically inhibit proton-gated current of ASIC1 isoform 1. Can increase inactivation speed of ASIC3. May be involved in regulation of proton sensing in dorsal root ganglions (By similarity). May play a role in protecting FBXW7 isoform 3 from degradation (PubMed:23082202).[UniProtKB/Swiss-Prot Function]

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