Human Cyclin E2 (CCNE2) activation kit by CRISPRa

CAT#: GA106087

CCNE2 CRISPRa kit - CRISPR gene activation of human cyclin E2



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

Product images

经常一起买 (3)
Rabbit Polyclonal Anti-CCNE2 Antibody
    • 100 ul

CNY 1,999.00
CNY 3,280.00


Lenti ORF particles, CCNE2 (Myc-DDK tagged) - Human cyclin E2 (CCNE2), 200ul, >10^7 TU/mL
    • 200 ul

CNY 8,455.00


Rabbit Polyclonal Cyclin E2 Antibody
    • 100 ug

CNY 5,302.00

Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol CCNE2
Locus ID 9134
Kit Components

GA106087G1, Cyclin E2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA106087G2, Cyclin E2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA106087G3, Cyclin E2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_004702, NM_057735, NM_057749
Synonyms CYCE2; cyclin E2; G1/S-specific cyclin E2
Summary The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK2. This cyclin has been shown to specifically interact with CIP/KIP family of CDK inhibitors, and plays a role in cell cycle G1/S transition. The expression of this gene peaks at the G1-S phase and exhibits a pattern of tissue specificity distinct from that of cyclin E1. A significantly increased expression level of this gene was observed in tumor-derived cells. [provided by RefSeq, Jul 2008]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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