Human AP1S2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	AP1S2
Locus ID	8905
Kit Components	GA105933G1, AP1S2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA105933G2, AP1S2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA105933G3, AP1S2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001272071, NM_003916, NM_001369007, NM_001369008, NR_160932, NR_160933, NM_001368994
Synonyms	DC22; MRX59; MRXS5; MRXS21; MRXSF; PGS; SIGMA1B
Summary	Adaptor protein complex 1 is found at the cytoplasmic face of coated vesicles located at the Golgi complex, where it mediates both the recruitment of clathrin to the membrane and the recognition of sorting signals within the cytosolic tails of transmembrane receptors. This complex is a heterotetramer composed of two large, one medium, and one small adaptin subunit. The protein encoded by this gene serves as the small subunit of this complex and is a member of the adaptin protein family. Transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2013]

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