Human EIF2B4 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	EIF2B4
Locus ID	8890
Kit Components	GA105921G1, EIF2B4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA105921G2, EIF2B4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA105921G3, EIF2B4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001034116, NM_001318965, NM_001318966, NM_001318967, NM_001318968, NM_001318969, NM_015636, NM_172195
Synonyms	EIF-2B; EIF2B; EIF2Bdelta
Summary	Eukaryotic initiation factor 2B (EIF2B), which is necessary for protein synthesis, is a GTP exchange factor composed of five different subunits. The protein encoded by this gene is the fourth, or delta, subunit. Defects in this gene are a cause of leukoencephalopathy with vanishing white matter (VWM) and ovarioleukodystrophy. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

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