Human DPM1 activation kit by CRISPRa

CAT#: GA105857

DPM1 CRISPRa kit - CRISPR gene activation of human dolichyl-phosphate mannosyltransferase subunit 1, catalytic



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

Product images

经常一起买 (2)
DPM1 Rabbit polyclonal Antibody
    • 100 ul

CNY 1,999.00
CNY 3,280.00


DPM1 (Myc-DDK-tagged)-Human dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit (DPM1)
    • 10 ug

CNY 2,400.00
CNY 3,705.00

Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol DPM1
Locus ID 8813
Kit Components

GA105857G1, DPM1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA105857G2, DPM1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA105857G3, DPM1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001317034, NM_001317035, NM_001317036, NM_003859, NR_133648
Synonyms CDGIE; MPDS
Summary Dolichol-phosphate mannose (Dol-P-Man) serves as a donor of mannosyl residues on the lumenal side of the endoplasmic reticulum (ER). Lack of Dol-P-Man results in defective surface expression of GPI-anchored proteins. Dol-P-Man is synthesized from GDP-mannose and dolichol-phosphate on the cytosolic side of the ER by the enzyme dolichyl-phosphate mannosyltransferase. Human DPM1 lacks a carboxy-terminal transmembrane domain and signal sequence and is regulated by DPM2. Mutations in this gene are associated with congenital disorder of glycosylation type Ie. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2015]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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