Human NCOA1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	NCOA1
Locus ID	8648
Kit Components	GA105731G1, NCOA1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA105731G2, NCOA1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA105731G3, NCOA1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_003743, NM_147223, NM_147233, NM_001362950, NM_001362952, NM_001362954, NM_001362955
Synonyms	bHLHe42; bHLHe74; F-SRC-1; KAT13A; RIP160; SRC1
Summary	The protein encoded by this gene acts as a transcriptional coactivator for steroid and nuclear hormone receptors. It is a member of the p160/steroid receptor coactivator (SRC) family and like other family members has histone acetyltransferase activity and contains a nuclear localization signal, as well as bHLH and PAS domains. The product of this gene binds nuclear receptors directly and stimulates the transcriptional activities in a hormone-dependent fashion. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]

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