Human PARG activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	PARG
Locus ID	8505
Kit Components	GA105623G1, PARG gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA105623G2, PARG gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA105623G3, PARG gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001303486, NM_001303487, NM_001303489, NM_001324381, NM_003631, NR_130168, NR_130169, NR_136752, NR_136753, NR_136754, NR_136755, NR_136756
Synonyms	PARG99
Summary	Poly(ADP-ribose) glycohydrolase (PARG) is the major enzyme responsible for the catabolism of poly(ADP-ribose), a reversible covalent-modifier of chromosomal proteins. The protein is found in many tissues and may be subject to proteolysis generating smaller, active products. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2015]

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