Human PI 3 Kinase p55 gamma (PIK3R3) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	PIK3R3
Locus ID	8503
Kit Components	GA105621G1, PI 3 Kinase p55 gamma gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA105621G2, PI 3 Kinase p55 gamma gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA105621G3, PI 3 Kinase p55 gamma gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001114172, NM_001303428, NM_001303429, NM_001328648, NM_001328649, NM_001328650, NM_001328651, NM_001328652, NM_001328653, NM_001328654, NM_003629, NR_137329
Synonyms	p55; p55-GAMMA; p55PIK
Summary	Phosphatidylinositol 3-kinase (PI3K) phosphorylates phosphatidylinositol and similar compounds, which then serve as second messengers in growth signaling pathways. PI3K is composed of a catalytic and a regulatory subunit. The protein encoded by this gene represents a regulatory subunit of PI3K. The encoded protein contains two SH2 domains through which it binds activated protein tyrosine kinases to regulate their activity. [provided by RefSeq, Jun 2016]

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