Human Liprin alpha 2 (PPFIA2) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	PPFIA2
Locus ID	8499
Kit Components	GA105617G1, Liprin alpha 2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA105617G2, Liprin alpha 2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA105617G3, Liprin alpha 2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001220473, NM_001220474, NM_001220475, NM_001220476, NM_001220477, NM_001220478, NM_001220479, NM_001220480, NM_001282536, NM_003625, NR_038265
Synonyms	FLJ41378; MGC132572
Summary	The protein encoded by this gene is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. It has been proposed that liprins are multivalent proteins that form complex structures and act as scaffolds for the recruitment and anchoring of LAR family of tyrosine phosphatases. This protein has been shown to bind the calcium/calmodulin-dependent serine protein kinase (MAGUK family) protein (also known as CASK) and proposed to regulate higher-order brain functions in mammals. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]

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