Human WHSC1 activation kit by CRISPRa
CAT#: GA105145
NSD2 CRISPRa kit - CRISPR gene activation of human nuclear receptor binding SET domain protein 2
CNY 12,255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | NSD2 |
Locus ID | 7468 |
Kit Components | GA105145G1, WHSC1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA105145G2, WHSC1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA105145G3, WHSC1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_001042424, NM_007331, NM_014919, NM_133330, NM_133331, NM_133332, NM_133333, NM_133334, NM_133335, NM_133336 |
Synonyms | MMSET; NSD2; REIIBP; TRX5; WHS |
Summary | This gene encodes a protein that contains four domains present in other developmental proteins: a PWWP domain, an HMG box, a SET domain, and a PHD-type zinc finger. It is expressed ubiquitously in early development. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4. This gene maps to the 165 kb WHS critical region and has also been involved in the chromosomal translocation t(4;14)(p16.3;q32.3) in multiple myelomas. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. Some transcript variants are nonsense-mediated mRNA (NMD) decay candidates, hence not represented as reference sequences. [provided by RefSeq, Jul 2008] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN412349 | NSD2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
CNY 8,680.00 |