Human Thimet Oligopeptidase (THOP1) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	THOP1
Locus ID	7064
Kit Components	GA104868G1, Thimet Oligopeptidase gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA104868G2, Thimet Oligopeptidase gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA104868G3, Thimet Oligopeptidase gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_003249
Synonyms	EP24.15; MEPD_HUMAN; MP78; TOP
Summary	The protein encoded by this gene is a kininase that uses zinc as a cofactor. The encoded oligopeptidase cleaves cytosolic peptides, making them unavailable for display on antigen-presenting cells. This protein also cleaves neuropeptides under 20 aa in length and can degrade beta-amyloid precursor protein to amyloidogenic peptides. [provided by RefSeq, Nov 2015]

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