Human mtTFA (TFAM) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	TFAM
Locus ID	7019
Kit Components	GA104828G1, mtTFA gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA104828G2, mtTFA gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA104828G3, mtTFA gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001270782, NM_003201, NM_012251, NR_073073
Synonyms	MTTF1; MTTFA; TCF6; TCF6L1; TCF6L2; TCF6L3
Summary	This gene encodes a key mitochondrial transcription factor containing two high mobility group motifs. The encoded protein also functions in mitochondrial DNA replication and repair. Sequence polymorphisms in this gene are associated with Alzheimer's and Parkinson's diseases. There are pseudogenes for this gene on chromosomes 6, 7, and 11. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]

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