Human Treacher Collins syndrome protein (TCOF1) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	TCOF1
Locus ID	6949
Kit Components	GA104797G1, Treacher Collins syndrome protein gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA104797G2, Treacher Collins syndrome protein gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA104797G3, Treacher Collins syndrome protein gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_000356, NM_001008656, NM_001008657, NM_001135243, NM_001135244, NM_001135245, NM_001195141
Synonyms	MFD1; TCS; TCS1; treacle
Summary	This gene encodes a nucleolar protein with a LIS1 homology domain. The protein is involved in ribosomal DNA gene transcription through its interaction with upstream binding factor (UBF). Mutations in this gene have been associated with Treacher Collins syndrome, a disorder which includes abnormal craniofacial development. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008]

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.