Human HNF1 beta (HNF1B) activation kit by CRISPRa

CAT#: GA104781

HNF1B CRISPRa kit - CRISPR gene activation of human HNF1 homeobox B



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

Product images

经常一起买 (3)
Rabbit polyclonal HNF1B Antibody
    • 100 ul

CNY 1,999.00
CNY 2,700.00


HNF1B (Myc-DDK-tagged)-Human HNF1 homeobox B (HNF1B), transcript variant 1
    • 10 ug

CNY 4,152.00
CNY 4,560.00


Rabbit polyclonal HNF1B Antibody
    • 30 ul

CNY 800.00

Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol HNF1B
Locus ID 6928
Kit Components

GA104781G1, HNF1 beta gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA104781G2, HNF1 beta gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA104781G3, HNF1 beta gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_000458, NM_001165923, NM_001304286, NM_006481
Synonyms FJHN; HNF-1-beta; HNF-1B; HNF1beta; HNF2; HPC11; LF-B3; LFB3; MODY5; TCF-2; TCF2; VHNF1
Summary This gene encodes a member of the homeodomain-containing superfamily of transcription factors. The protein binds to DNA as either a homodimer, or a heterodimer with the related protein hepatocyte nuclear factor 1-alpha. The gene has been shown to function in nephron development, and regulates development of the embryonic pancreas. Mutations in this gene result in renal cysts and diabetes syndrome and noninsulin-dependent diabetes mellitus, and expression of this gene is altered in some types of cancer. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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