Human Munc18c (STXBP3) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	STXBP3
Locus ID	6814
Kit Components	GA104689G1, Munc18c gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA104689G2, Munc18c gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA104689G3, Munc18c gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_007269
Synonyms	MUNC18-3; MUNC18C; PSP; UNC-18C
Summary	Together with STX4 and VAMP2, may play a role in insulin-dependent movement of GLUT4 and in docking/fusion of intracellular GLUT4-containing vesicles with the cell surface in adipocytes.[UniProtKB/Swiss-Prot Function]

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