Human Munc18 1 (STXBP1) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	STXBP1
Locus ID	6812
Kit Components	GA104687G1, Munc18 1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA104687G2, Munc18 1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA104687G3, Munc18 1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001032221, NM_003165
Synonyms	MUNC18-1; NSEC1; P67; RBSEC1; UNC18
Summary	This gene encodes a syntaxin-binding protein. The encoded protein appears to play a role in release of neurotransmitters via regulation of syntaxin, a transmembrane attachment protein receptor. Mutations in this gene have been associated with infantile epileptic encephalopathy-4. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2010]

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