Human SON activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	SON
Locus ID	6651
Kit Components	GA104561G1, SON gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA104561G2, SON gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA104561G3, SON gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001291411, NM_001291412, NM_003103, NM_032195, NM_058183, NM_138925, NM_138926, NM_138927, NR_103796, NR_103797, NR_103798
Synonyms	BASS1; C21orf50; DBP-5; NREBP; SON3
Summary	This gene encodes a protein that contains multiple simple repeats. The encoded protein binds RNA and promotes pre-mRNA splicing, particularly of transcripts with poor splice sites. The protein also recognizes a specific DNA sequence found in the human hepatitis B virus (HBV) and represses HBV core promoter activity. There is a pseudogene for this gene on chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]

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