Human SNRP70 (SNRNP70) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	SNRNP70
Locus ID	6625
Kit Components	GA104538G1, SNRP70 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA104538G2, SNRP70 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA104538G3, SNRP70 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001009820, NM_001301069, NM_003089
Synonyms	RNPU1Z; RPU1; U1AP; U1RNP; U170K
Summary	Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome (PubMed:19325628, PubMed:25555158). SNRNP70 binds to the loop I region of U1-snRNA (PubMed:2467746, PubMed:19325628, PubMed:25555158).[UniProtKB/Swiss-Prot Function]

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