Human beta Synuclein (SNCB) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	SNCB
Locus ID	6620
Kit Components	GA104533G1, beta Synuclein gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA104533G2, beta Synuclein gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA104533G3, beta Synuclein gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001001502, NM_001318034, NM_001318035, NM_001318036, NM_001318037, NM_003085, NM_001363140
Synonyms	beta-synuclein; synuclein, beta
Summary	This gene encodes a member of a small family of proteins that inhibit phospholipase D2 and may function in neuronal plasticity. The encoded protein is abundant in lesions of patients with Alzheimer disease. A mutation in this gene was found in individuals with dementia with Lewy bodies. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]

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