Human SHB activation kit by CRISPRa
CAT#: GA104398
SHB CRISPRa kit - CRISPR gene activation of human SH2 domain containing adaptor protein B
CNY 12,255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | SHB |
Locus ID | 6461 |
Kit Components | GA104398G1, SHB gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA104398G2, SHB gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA104398G3, SHB gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_003028 |
Synonyms | bA3J10.2 |
Summary | Adapter protein which regulates several signal transduction cascades by linking activated receptors to downstream signaling components. May play a role in angiogenesis by regulating FGFR1, VEGFR2 and PDGFR signaling. May also play a role in T-cell antigen receptor/TCR signaling, interleukin-2 signaling, apoptosis and neuronal cells differentiation by mediating basic-FGF and NGF-induced signaling cascades. May also regulate IRS1 and IRS2 signaling in insulin-producing cells.[UniProtKB/Swiss-Prot Function] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN422156 | SHB - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
CNY 8,680.00 |