Human MDC (CCL22) activation kit by CRISPRa

CAT#: GA104329

CCL22 CRISPRa kit - CRISPR gene activation of human C-C motif chemokine ligand 22



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

Product images

经常一起买 (3)
CCL22 rabbit polyclonal antibody
    • 100 ul

CNY 1,999.00
CNY 3,280.00


CCL22 (Myc-DDK-tagged)-Human chemokine (C-C motif) ligand 22 (CCL22)
    • 10 ug

CNY 1,200.00
CNY 3,705.00


CCL22 rabbit polyclonal antibody
    • 25 ul

CNY 800.00
CNY 1,280.00

Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol CCL22
Locus ID 6367
Kit Components

GA104329G1, MDC gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA104329G2, MDC gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA104329G3, MDC gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_002990
Synonyms A-152E5.1; ABCD-1; DC/B-CK; MDC; SCYA22; STCP-1
Summary This antimicrobial gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 16. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for monocytes, dendritic cells, natural killer cells and for chronically activated T lymphocytes. It also displays a mild activity for primary activated T lymphocytes and has no chemoattractant activity for neutrophils, eosinophils and resting T lymphocytes. The product of this gene binds to chemokine receptor CCR4. This chemokine may play a role in the trafficking of activated T lymphocytes to inflammatory sites and other aspects of activated T lymphocyte physiology. [provided by RefSeq, Sep 2014]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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