Human SCNN1D activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	SCNN1D
Locus ID	6339
Kit Components	GA104304G1, SCNN1D gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA104304G2, SCNN1D gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA104304G3, SCNN1D gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001130413, NM_002978, NR_037668
Synonyms	dNaCh; ENaCd; ENaCdelta; SCNED
Summary	Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception.[UniProtKB/Swiss-Prot Function]

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