Human Retinoblastoma binding protein 6 (RBBP6) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	RBBP6
Locus ID	5930
Kit Components	GA104040G1, Retinoblastoma binding protein 6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA104040G2, Retinoblastoma binding protein 6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA104040G3, Retinoblastoma binding protein 6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_006910, NM_018703, NM_032626
Synonyms	MY038; P2P-R; PACT; RBQ-1; SNAMA
Summary	The retinoblastoma tumor suppressor (pRB) protein binds with many other proteins. In various human cancers, pRB suppresses cellular proliferation and is inactivated. Cell cycle-dependent phosphorylation regulates the activity of pRB. This gene encodes a protein which binds to underphosphorylated but not phosphorylated pRB. Multiple alternatively spliced transcript variants that encode different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

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