Human Germinal Center Kinase (MAP4K2) activation kit by CRISPRa
CAT#: GA103985
MAP4K2 CRISPRa kit - CRISPR gene activation of human mitogen-activated protein kinase kinase kinase kinase 2
CNY 12,255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | MAP4K2 |
Locus ID | 5871 |
Kit Components | GA103985G1, Germinal Center Kinase gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA103985G2, Germinal Center Kinase gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA103985G3, Germinal Center Kinase gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_001307990, NM_004579 |
Synonyms | BL44; GCK; RAB8IP |
Summary | The protein encoded by this gene is a member of the serine/threonine protein kinase family. Although this kinase is found in many tissues, its expression in lymphoid follicles is restricted to the cells of germinal centre, where it may participate in B-cell differentiation. This kinase can be activated by TNF-alpha, and has been shown to specifically activate MAP kinases. This kinase is also found to interact with TNF receptor-associated factor 2 (TRAF2), which is involved in the activation of MAP3K1/MEKK1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN417608 | MAP4K2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
CNY 8,680.00 |