Human PTP alpha (PTPRA) activation kit by CRISPRa

CAT#: GA103930

PTPRA CRISPRa kit - CRISPR gene activation of human protein tyrosine phosphatase receptor type A



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

Product images

经常一起买 (3)
PTPRA Rabbit polyclonal Antibody
    • 100 ul

CNY 1,999.00
CNY 3,280.00


PTPRA (Myc-DDK-tagged)-Human protein tyrosine phosphatase, receptor type, A (PTPRA), transcript variant 3
    • 10 ug

CNY 5,808.00


Phospho-PTPRA-Y789 Rabbit polyclonal Antibody
    • 100 ul

CNY 2,900.00

Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol PTPRA
Locus ID 5786
Kit Components

GA103930G1, PTP alpha gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA103930G2, PTP alpha gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA103930G3, PTP alpha gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_002836, NM_080840, NM_080841
Synonyms HEPTP; HLPR; HPTPA; HPTPalpha; LRP; PTPA; PTPRL2; R-PTP-alpha; RPTPA
Summary The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. This PTP has been shown to dephosphorylate and activate Src family tyrosine kinases, and is implicated in the regulation of integrin signaling, cell adhesion and proliferation. Three alternatively spliced variants of this gene, which encode two distinct isoforms, have been reported. [provided by RefSeq, Jul 2008]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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