Human PSMC3 activation kit by CRISPRa

CAT#: GA103871

PSMC3 CRISPRa kit - CRISPR gene activation of human proteasome 26S subunit, ATPase 3



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

Product images

经常一起买 (3)
Anti-PSMC3 mouse monoclonal antibody, clone OTI9F3 (formerly 9F3)
    • 100 ul

CNY 1,999.00
CNY 2,700.00


PSMC3 (Myc-DDK-tagged)-Human proteasome (prosome, macropain) 26S subunit, ATPase, 3 (PSMC3)
    • 10 ug

CNY 3,656.00
CNY 3,990.00


PSMC3 mouse monoclonal antibody,clone OTI8D2
    • 30 ul

CNY 800.00

Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol PSMC3
Locus ID 5702
Kit Components

GA103871G1, PSMC3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA103871G2, PSMC3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA103871G3, PSMC3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_002804
Synonyms TBP1
Summary The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases that have chaperone-like activity. This subunit may compete with PSMC2 for binding to the HIV tat protein to regulate the interaction between the viral protein and the transcription complex. A pseudogene has been identified on chromosome 9. [provided by RefSeq, Jul 2008]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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