Human PRELP activation kit by CRISPRa

CAT#: GA103745

PRELP CRISPRa kit - CRISPR gene activation of human proline and arginine rich end leucine rich repeat protein



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

Product images

经常一起买 (3)
Rabbit polyclonal PRELP Antibody (C-term)
    • 400 ul

CNY 6,160.00


PRELP (Myc-DDK-tagged)-Human proline/arginine-rich end leucine-rich repeat protein (PRELP), transcript variant 2
    • 10 ug

CNY 3,656.00
CNY 3,990.00


PRELP Rabbit polyclonal Antibody
    • 100 ul

CNY 1,999.00
CNY 3,280.00

Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol PRELP
Locus ID 5549
Kit Components

GA103745G1, PRELP gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA103745G2, PRELP gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA103745G3, PRELP gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_002725, NM_201348
Synonyms MST161; MSTP161; SLRR2A
Summary The protein encoded by this gene is a leucine-rich repeat protein present in connective tissue extracellular matrix. This protein functions as a molecule anchoring basement membranes to the underlying connective tissue. This protein has been shown to bind type I collagen to basement membranes and type II collagen to cartilage. It also binds the basement membrane heparan sulfate proteoglycan perlecan. This protein is suggested to be involved in the pathogenesis of Hutchinson-Gilford progeria (HGP), which is reported to lack the binding of collagen in basement membranes and cartilage. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq, Jul 2008]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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