Human Pancreatic Polypeptide (PPY) activation kit by CRISPRa

CAT#: GA103738

PPY CRISPRa kit - CRISPR gene activation of human pancreatic polypeptide



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

Product images

经常一起买 (3)
PPY mouse monoclonal antibody,clone OTI1G2
    • 100 ul

CNY 1,999.00
CNY 3,490.00


PPY (Myc-DDK-tagged)-Human pancreatic polypeptide (PPY)
    • 10 ug

CNY 1,800.00
CNY 3,705.00


PPY mouse monoclonal antibody,clone OTI1G2
    • 30 ul

CNY 800.00

Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol PPY
Locus ID 5539
Kit Components

GA103738G1, Pancreatic Polypeptide gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA103738G2, Pancreatic Polypeptide gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA103738G3, Pancreatic Polypeptide gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001319209, NM_002722
Synonyms PNP
Summary This gene encodes a member of the neuropeptide Y (NPY) family of peptides. The encoded 95 aa preproprotein is synthesized in the pancreatic islets of Langerhans and proteolytically processed to generate two peptide products. These products include the active pancreatic hormone of 36 aa and an icosapeptide of unknown function. This hormone acts as a regulator of pancreatic and gastrointestinal functions and may be important in the regulation of food intake. Plasma level of this hormone has been shown to be reduced in conditions associated with increased food intake and elevated in anorexia nervosa. In addition, infusion of this hormone in obese rodents has shown to decrease weight gain. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Jan 2016]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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