Human Phospholipase D1 (PLD1) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	PLD1
Locus ID	5337
Kit Components	GA103597G1, Phospholipase D1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA103597G2, Phospholipase D1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA103597G3, Phospholipase D1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001130081, NM_002662
Synonyms	Phoshpolipase D gene 1 probably with two splicing variants A and B; phospholipase D1; phospholipase D gene 1, probably with two splicing variants A and B; Pld1a; Pld1b; Plda; Pldb
Summary	This gene encodes a phosphatidylcholine-specific phospholipase which catalyzes the hydrolysis of phosphatidylcholine in order to yield phosphatidic acid and choline. The enzyme may play a role in signal transduction and subcellular trafficking. Alternative splicing results in multiple transcript variants with both catalytic and regulatory properties. [provided by RefSeq, Sep 2011]

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