Human PIGA activation kit by CRISPRa

CAT#: GA103546

PIGA CRISPRa kit - CRISPR gene activation of human phosphatidylinositol glycan anchor biosynthesis class A



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

Product images

经常一起买 (3)
PIGA Antibody - middle region
    • 100 ul

CNY 5,250.00


PIGA (Myc-DDK-tagged)-Human phosphatidylinositol glycan anchor biosynthesis, class A (PIGA), transcript variant 1
    • 10 ug

CNY 3,656.00
CNY 3,990.00


PIGA Antibody - middle region
    • 100 ul

CNY 5,250.00

Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol PIGA
Locus ID 5277
Kit Components

GA103546G1, PIGA gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA103546G2, PIGA gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA103546G3, PIGA gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_002641, NM_020472, NM_020473, NR_033835, NR_033836
Synonyms GPI3; MCAHS2; PIG-A; PNH1
Summary This gene encodes a protein required for synthesis of N-acetylglucosaminyl phosphatidylinositol (GlcNAc-PI), the first intermediate in the biosynthetic pathway of GPI anchor. The GPI anchor is a glycolipid found on many blood cells and which serves to anchor proteins to the cell surface. Paroxysmal nocturnal hemoglobinuria, an acquired hematologic disorder, has been shown to result from mutations in this gene. Alternate splice variants have been characterized. A related pseudogene is located on chromosome 12. [provided by RefSeq, Jun 2010]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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