Human PDE4D activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	PDE4D
Locus ID	5144
Kit Components	GA103441G1, PDE4D gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA103441G2, PDE4D gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA103441G3, PDE4D gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001104631, NM_001165899, NM_001197218, NM_001197219, NM_001197220, NM_001197221, NM_001197222, NM_001197223, NM_006203, NM_001349241, NM_001349242, NM_001349243, NM_001364599, NM_001364600, NM_001364602, NM_001364601, NM_001364603, NM_001364604
Synonyms	ACRDYS2; DPDE3; HSPDE4D; PDE4DN2; PDE43; STRK1
Summary	This gene encodes one of four mammalian counterparts to the fruit fly 'dunce' gene. The encoded protein has 3',5'-cyclic-AMP phosphodiesterase activity and degrades cAMP, which acts as a signal transduction molecule in multiple cell types. This gene uses different promoters to generate multiple alternatively spliced transcript variants that encode functional proteins.[provided by RefSeq, Sep 2009]

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