Human DMT1 (SLC11A2) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	SLC11A2
Locus ID	4891
Kit Components	GA103266G1, DMT1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA103266G2, DMT1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA103266G3, DMT1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_000617, NM_001174125, NM_001174126, NM_001174127, NM_001174128, NM_001174129, NM_001174130, NR_033421, NR_033422
Synonyms	DCT1; DMT1; NRAMP2
Summary	This gene encodes a member of the solute carrier family 11 protein family. The product of this gene transports divalent metals and is involved in iron absorption. Mutations in this gene are associated with hypochromic microcytic anemia with iron overload. A related solute carrier family 11 protein gene is located on chromosome 2. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Apr 2010]

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