Human NOP2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	NOP2
Locus ID	4839
Kit Components	GA103230G1, NOP2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA103230G2, NOP2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA103230G3, NOP2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001033714, NM_001258308, NM_001258309, NM_001258310, NM_006170
Synonyms	NOL1; NOP120; NSUN1; p120
Summary	Involved in ribosomal large subunit assembly (PubMed:24120868). S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the C(5) position of cytosine 4447 in 28S rRNA (Probable). May play a role in the regulation of the cell cycle and the increased nucleolar activity that is associated with the cell proliferation (Probable).[UniProtKB/Swiss-Prot Function]

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