Human NEK1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	NEK1
Locus ID	4750
Kit Components	GA103168G1, NEK1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA103168G2, NEK1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA103168G3, NEK1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001199397, NM_001199398, NM_001199399, NM_001199400, NM_012224
Synonyms	NY-REN-55; SRPS2; SRPS2A; SRTD6
Summary	The protein encoded by this gene is a serine/threonine kinase involved in cell cycle regulation. The encoded protein is found in a centrosomal complex with FEZ1, a neuronal protein that plays a role in axonal development. Defects in this gene are a cause of polycystic kidney disease (PKD). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2010]

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