Human Neurofilament (NEFL) activation kit by CRISPRa

CAT#: GA103167

NEFL CRISPRa kit - CRISPR gene activation of human neurofilament light



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

Product images

经常一起买 (3)
NEFL mouse monoclonal antibody,clone OTI3G2
    • 100 ul

CNY 1,999.00
CNY 2,700.00


NEFL (Myc-DDK-tagged)-Human neurofilament, light polypeptide (NEFL)
    • 10 ug

CNY 6,064.00


NEFL mouse monoclonal antibody, clone OTI14B10
    • 30 ul

CNY 800.00

Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol NEFL
Locus ID 4747
Kit Components

GA103167G1, Neurofilament gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA103167G2, Neurofilament gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA103167G3, Neurofilament gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_006158
Synonyms CMT1F; CMT2E; NF-L; NF68; NFL; PPP1R110
Summary Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y. [provided by RefSeq, Oct 2008]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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