Human Lactate Dehydrogenase B (LDHB) activation kit by CRISPRa

CAT#: GA102673

LDHB CRISPRa kit - CRISPR gene activation of human lactate dehydrogenase B



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

Product images

经常一起买 (3)
Rabbit Polyclonal Anti-LDHB Antibody
    • 100 ul

CNY 5,250.00


LDHB (Myc-DDK-tagged)-Human lactate dehydrogenase B (LDHB), transcript variant 1
    • 10 ug

CNY 5,488.00


LDHB Rabbit polyclonal Antibody
    • 100 ul

CNY 1,999.00
CNY 3,280.00

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Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol LDHB
Locus ID 3945
Kit Components

GA102673G1, Lactate Dehydrogenase B gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA102673G2, Lactate Dehydrogenase B gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA102673G3, Lactate Dehydrogenase B gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001174097, NM_002300, NM_001315537
Synonyms HEL-S-281; LDH-B; LDH-H; LDHBD; TRG-5
Summary This gene encodes the B subunit of lactate dehydrogenase enzyme, which catalyzes the interconversion of pyruvate and lactate with concomitant interconversion of NADH and NAD+ in a post-glycolysis process. Alternatively spliced transcript variants have been found for this gene. Recent studies have shown that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism, and that this isoform is localized in the peroxisomes. Mutations in this gene are associated with lactate dehydrogenase B deficiency. Pseudogenes have been identified on chromosomes X, 5 and 13. [provided by RefSeq, Feb 2016]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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