Human KCNMA1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	KCNMA1
Locus ID	3778
Kit Components	GA102552G1, KCNMA1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA102552G2, KCNMA1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA102552G3, KCNMA1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001014797, NM_001161352, NM_001161353, NM_001271518, NM_001271519, NM_001271520, NM_001271521, NM_001271522, NM_001322829, NM_001322830, NM_001322832, NM_001322835, NM_001322836, NM_001322837, NM_001322838, NM_001322839, NM_002247
Synonyms	bA205K10.1; BKTM; hSlo; KCa1.1; MaxiK; mSLO1; SAKCA; SLO; SLO-ALPHA; SLO1
Summary	MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit, which is the product of this gene, and the modulatory beta subunit. Intracellular calcium regulates the physical association between the alpha and beta subunits. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]

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