Human IVD activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	IVD
Locus ID	3712
Kit Components	GA102499G1, IVD gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA102499G2, IVD gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA102499G3, IVD gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001159508, NM_002225, NM_001354597, NM_001354598, NM_001354599, NM_001354600, NM_001354601, NR_148923, NR_148924, NR_148925
Synonyms	ACAD2
Summary	Isovaleryl-CoA dehydrogenase (IVD) is a mitochondrial matrix enzyme that catalyzes the third step in leucine catabolism. The genetic deficiency of IVD results in an accumulation of isovaleric acid, which is toxic to the central nervous system and leads to isovaleric acidemia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2017]

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