Human IKK beta (IKBKB) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	IKBKB
Locus ID	3551
Kit Components	GA102370G1, IKK beta gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA102370G2, IKK beta gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA102370G3, IKK beta gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001190720, NM_001190721, NM_001190722, NM_001242778, NM_001556, NR_033818, NR_033819, NR_033820, NR_040009
Synonyms	IKK-beta; IKK2; IKKB; IMD15; NFKBIKB
Summary	The protein encoded by this gene phosphorylates the inhibitor in the inhibitor/NF-kappa-B complex, causing dissociation of the inhibitor and activation of NF-kappa-B. The encoded protein itself is found in a complex of proteins. Several transcript variants, some protein-coding and some not, have been found for this gene. [provided by RefSeq, Sep 2011]

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