Human 5HT4 Receptor (HTR4) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	HTR4
Locus ID	3360
Kit Components	GA102288G1, 5HT4 Receptor gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA102288G2, 5HT4 Receptor gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA102288G3, 5HT4 Receptor gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_000870, NM_001040169, NM_001040171, NM_001040172, NM_001040173, NM_001040174, NM_001286410, NM_199453, NR_104445
Synonyms	5-HT4; 5-HT4R
Summary	This gene is a member of the family of serotonin receptors, which are G protein coupled receptors that stimulate cAMP production in response to serotonin (5-hydroxytryptamine). The gene product is a glycosylated transmembrane protein that functions in both the peripheral and central nervous system to modulate the release of various neurotransmitters. Multiple transcript variants encoding proteins with distinct C-terminal sequences have been described. [provided by RefSeq, May 2010]

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