Human Hydroxysteroid (17 beta) Dehydrogenase 4 (HSD17B4) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	HSD17B4
Locus ID	3295
Kit Components	GA102250G1, Hydroxysteroid (17 beta) Dehydrogenase 4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA102250G2, Hydroxysteroid (17 beta) Dehydrogenase 4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA102250G3, Hydroxysteroid (17 beta) Dehydrogenase 4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_000414, NM_001199291, NM_001199292, NM_001292027, NM_001292028
Synonyms	DBP; MFE-2; MPF-2; PRLTS1; SDR8C1
Summary	The protein encoded by this gene is a bifunctional enzyme that is involved in the peroxisomal beta-oxidation pathway for fatty acids. It also acts as a catalyst for the formation of 3-ketoacyl-CoA intermediates from both straight-chain and 2-methyl-branched-chain fatty acids. Defects in this gene that affect the peroxisomal fatty acid beta-oxidation activity are a cause of D-bifunctional protein deficiency (DBPD). An apparent pseudogene of this gene is present on chromosome 8. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014]

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.