Human Prostaglandin dehydrogenase 1 (HPGD) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	HPGD
Locus ID	3248
Kit Components	GA102225G1, Prostaglandin dehydrogenase 1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA102225G2, Prostaglandin dehydrogenase 1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA102225G3, Prostaglandin dehydrogenase 1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_000860, NM_001145816, NM_001256301, NM_001256305, NM_001256306, NM_001256307, NR_027332, NM_001363574
Synonyms	15-PGDH; PGDH; PGDH1; PHOAR1; SDR36C1
Summary	This gene encodes a member of the short-chain nonmetalloenzyme alcohol dehydrogenase protein family. The encoded enzyme is responsible for the metabolism of prostaglandins, which function in a variety of physiologic and cellular processes such as inflammation. Mutations in this gene result in primary autosomal recessive hypertrophic osteoarthropathy and cranioosteoarthropathy. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]

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