Human HNRPH1 (HNRNPH1) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	HNRNPH1
Locus ID	3187
Kit Components	GA102175G1, HNRPH1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA102175G2, HNRPH1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA102175G3, HNRPH1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001257293, NM_005520, NM_001364233, NM_001363572, NM_001364227, NM_001364228, NM_001364234, NM_001364236, NM_001364237, NM_001364239, NM_001364242, NM_001364244, NM_001364245, NM_001364247, NM_001364251, NM_001364252, NM_001364253, NM_001364255, NM_001364225, NM_001364226, NM_001364229, NM_001364230, NM_001364231, NM_001364232, NM_001364235, NM_001364238, NM_001364240, NM_001364241, NM_001364243, NM_001364246, NM_001364248, NM_001364250, NM_001364254
Synonyms	hnRNPH; HNRPH; HNRPH1
Summary	This gene encodes a member of a subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins that complex with heterogeneous nuclear RNA. These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some may shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNA and is very similar to the family member HNRPF. This gene may be associated with hereditary lymphedema type I. Alternatively spliced transcript variants have been described [provided by RefSeq, Mar 2012]

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