Human NUR77 (NR4A1) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	NR4A1
Locus ID	3164
Kit Components	GA102158G1, NUR77 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA102158G2, NUR77 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA102158G3, NUR77 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001202233, NM_001202234, NM_002135, NM_173157, NM_173158
Synonyms	GFRP1; HMR; N10; NAK-1; NGFIB; NP10; NUR77; TR3
Summary	This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. Expression is induced by phytohemagglutinin in human lymphocytes and by serum stimulation of arrested fibroblasts. The encoded protein acts as a nuclear transcription factor. Translocation of the protein from the nucleus to mitochondria induces apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2011]

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